Says the BBC: Scientific investigations during the experiment will assess the effect that isolation has on various psychological and physiological aspects such as stress, hormone levels, sleep quality, mood and the benefits of dietary supplements.
I can't tell if this is inspired more by scientific research or by reality TV.
Link: http://news.bbc.co.uk/2/hi/science_and_environment/10197470.stm
Also, a somewhat relevant New Yorker article: http://www.newyorker.com/reporting/2009/03/30/090330fa_fact_gawande

And this might lead to the first actual space-related murder on record! (The diaper wearing, cross-country astronaut lady failed in her murder attempt, so she loses the space-murder race. Next time, USA, next time).
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